Neuromyelitis optica spectrum disorder and varicella-zoster infection.
نویسندگان
چکیده
Neuromyelitis Optica (NMO) is an autoimmune condition that predominantly targets optic nerves and spinal cord. The discovery of NMO-IgG and its target aquaporin-4 (AQP4) as a marker of NMO allowed a better understanding of the disease and, recently, a new definition and diagnostic criteria for NMO spectrum diseases (NMOSD) have been proposed [1]. In a subgroup of patients with NMOSD, a parainfectious pathogenesis may play a central role [2].
منابع مشابه
Sjögren’s syndrome and Neuromyelitis Optica spectrum disorders (NMOSD) – a case report and review of literature
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Significant advances have been made in diagnosis and therapy of demyelinating disorders of the central nervous system. The most common entities of this disorders in adults – multiple sclerosis and neuromyelitis optica were initially thought to be different phenotypes of more or less the same disease. During the last ten years, this view was subsequently changed and the term neuromyelitis ...
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BACKGROUND A polyspecific, intrathecal humoral immune response against neurotropic viruses such as measles, rubella and varicella zoster virus (MRZ reaction, MRZR) is present in 80-100% of patients with multiple sclerosis (MS), but has not to date been evaluated in patients with neuromyelitis optica (NMO). AIMS To evaluate whether MRZR distinguishes NMO and MS. METHODS 20 patients with NMO ...
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ورودعنوان ژورنال:
- Journal of the neurological sciences
دوره 358 1-2 شماره
صفحات -
تاریخ انتشار 2015